The Showcase: Fix The Cell, The Science Behind Every Symptom

Most people spend years chasing symptoms. 

The fatigue. The brain fog. The inflammation that never fully settles. The recovery that takes longer than it should. And no matter what they try, something still feels off. 

What if all of it is pointing to the same place? 

In this special Showcase edition of Wellness Wednesday, we go deeper than we ever have before. We are talking about what is actually happening inside your cells and why three biological pathways, NRF2, NRF1 and NAD+, are the foundation of how you feel every single day. 

Joining us for this conversation is Dr. Nancy, a Doctor of Pharmacy with advanced degrees in biochemistry and pharmacology and a formulator on the LifeVantage Science Advisory Board. She has spent decades studying nutrigenomics and has a rare ability to take complex science and make it feel simple, relevant and actionable for everyday people. 

This one is not your typical wellness conversation. This is the science most people never hear outside of a research lab, explained in a way that will genuinely change how you think about your health. 

In this episode you will learn: 

What NRF2 is and why it is considered the master regulator of your body's internal defense system 

How NRF2 activation turns on your body's own antioxidant production including glutathione, superoxide dismutase and catalase rather than just adding antioxidants from the outside 

What oxidative stress actually is, why it builds up, and how it connects to inflammation, aging and the way you feel daily 

What NRF1 does for your mitochondria and why mitochondrial health is at the root of chronic fatigue and low energy 

Why NAD+ declines with age and what that means for your metabolism, your recovery, your mental clarity and your long-term cellular repair 

What happens when you support all three pathways together and why addressing them individually gives you a completely different result than supporting them as a system 

Why so many people are doing everything right on the surface and still not feeling their best, and what is actually missing at the cellular level 

How nutrigenomics is changing the way scientists and practitioners understand wellness, aging and what the body is capable of when it is properly supported 

Why fixing the cell is not about doing more but about going upstream to where every symptom actually begins 

About our guest: 

We are joined by Dr. Nancy, a Doctor of Pharmacy with expertise in biochemistry, pharmacology and nutrigenomics. She serves as a formulator on the LifeVantage Science Advisory Board and brings decades of experience in human and veterinary nutritional science to her work. Her mission is to help people understand how to support their body at the cellular level so they can feel their best and age with strength and clarity. 

Resources mentioned in this episode: 

• Protandim NRF2 Synergizer by LifeVantage 
• Protandim NRF1 Synergizer by LifeVantage 
• NAD Synergizer by LifeVantage 
• LifeVantage Science and Research Library available at lifevantage.com 

You can listen to all recordings via audio by visiting this link:

• https://biohackandactivate.com/activationpodcast

You can also find us on Apple Podcasts here:

• https://podcasts.apple.com/us/podcast/wellness-wednesday-activation-podcast/id1860715006

And on Spotify here:

• https://open.spotify.com/show/6wDumT9yTsCzNWD9LxzeIm

We release new episodes every week, so there is always fresh content to guide you on your wellness journey. Tune in, get inspired, and start supporting your body and mind from the inside out. 

Transcript

SPEAKER_00 0:01

Welcome everybody to a special episode of Wellness Wednesday. We call this the showcase. We are showcasing some incredible products tonight, all about cell health. We will talk about all three of these, but NRF2, NRF1, and NAD over the next half hour. But we believe at Wellness Wednesday truly that cell health is the foundation to elf. To age well, you fix the cell. To be well, you fix the cell. To live well, you fix the cell, right? My name is Shauna Mucklow, and I'm so happy to have you here. I come from Nebraska and I have been a wellness warrior for the last 10-ish years. From the Midwest, I'll be honest, wellness wasn't always on my mind. But when my doctor reached out to me 10 years ago to tell me about Protandum NRF2, she said, Listen, I think I've run across the future of wellness and you're gonna want to hear about this. And ever since it's led me down this path. I've taken it every day and I'll take it every day forever. And you'll understand why if you don't already. Or in fact, put a one in the chat if you already utilize Protandum NRF2 in your life. Just curious. Because I won't go a day without it after I knew what it does inside the body. There's no way you could get that out of my body ever. I love it so much. But it's led me down this path of discovery. I just want to constantly learn more, learn more. How do I optimize? How do I prevent? How do I do this? Right. And that has led me to some incredible relationships across the last 10 years of my life. And one of those being Dr. Nancy. She is one of the most brilliant people I have ever met and has become a sweet, sweet friend of mine. But Nancy, tell us a little bit about your background and what led you to loving this product line so much.

SPEAKER_01 1:50

Oh my goodness. Well, my background always was I'm a pharmacist and a doctor of pharmacology, but I had a degree in molecular biochemistry first before I went to pharmacy school. So because of that, I always understood the body from the cell out, if you will. And so I was always in search of trying to find better answers. And then a very, very severe illness happened. I won't go into all the details of it. Um, and here's the really important part a surfer. Okay, a surfer. Now he was a world-class surfer, okay. A surfer said, you know what? I want you to take a look at this. I think it might help you because I had a problem with something that doctors figured out was a gene problem. This is a while ago when no one talked about genes, right? And he said, take a look. And what brought me to the company was when of course he told me about it. I rolled my eyes, I'm like, okay, fine, whatever. But when I saw the science, the real science behind what we had, I was amazed because lots of pharmacology and pharmacy products are like that, because they can make the same thing over and over from synthetics and get the same results. But you don't see that in nutrients. And when I saw what we had based on why and how they did it, I I've been all in ever since. And I love it. It made a huge impact for me. So I'm so grateful to be here.

SPEAKER_00 3:29

I love it. And I I love your what you guys are gonna realize as we kind of go through these products tonight is layering them has an awesome effect for your body, even greater. Every time you layer another one on top of another one, there's a greater effect, and we're gonna talk about that. But I also love that we have have such passion for the cells being the foundation of health, right? And life vantage is the company behind these products, just so you know that. And but this is the reality. This is what Nancy was talking about, right? Like everyone is dealing with something, and it's likely because of our environment, right? We have to do something to clean up our cells, to help ourselves out, to boost them, to support them, and to activate them because we are like running into everything. The air we breathe, the water we drink, the food we're eating, right? The medicines and the pharmaceuticals we're putting inside of our bodies, nothing's helping ourselves. None of that is helping ourselves. They're hurting us. It's hurting us. And that's why people are starting to feel crummy, right? They're dealing with low energy, burnout, brain fog, mental fatigue, they're gaining weight, poor sleep. Like put a two in the chat if you or someone you know deals with something on this screen right now, right? Everyone, everyone I talk to is they're tired, they're overwhelmed, all the things. Well, here is the basic thought behind this. We're gonna work backwards, start at the bottom, right? That's what we feel. We feel aging, we feel disease, we feel fatigue, right? We feel all of those things, but really that is because of cellular damage. And how do our cells get damaged? Oxidative stress, mitochondrial decline, and NAB depletion. Those might all be brand new words to you. And if they are, we're gonna explain all of that because when that's happening, that causes cell damage, and that's what causes symptoms. Tonight we want to help you fix the symptoms, not mask them, fix them. We want to help you fix the cell, and these are the three products that are gonna help you do that, okay? We need solutions that work, period, and these do. Nancy said there's science behind every single one of the products we're gonna talk about, profound, amazing science, proven that they're gonna do what we say they're gonna do inside of your body, and you're gonna get the benefit. So let's dive in. Nancy, how is activation, which is how we describe these three products, so different than supplementation? I think you're muted, honey. But how how is activation so much different than supplementation? How do you describe that?

SPEAKER_01 6:02

There we go. There you go. Yay! Sorry about that. You know what? This is the part I was talking about the most, is having a molecular biochemistry background. It's all about the the cells having the ability to have proper nutrients and and and the proper chemistry going on, that when that happens, it it automatically balances the cell, right? And so when I saw the information on our NRF2 pro tandem, it it just was so eye-opening to me because it was something that for the first time I saw activation, it it wasn't a supplement. Think of it almost like homeopathy, teeny tiny amounts of something blended together to do something different. And that activation turns on our body's own ability. And you know what? God knows way more than we do. And the things that turn out from that are just incredible. And that for me, the difference between supplementation and activation was what really brought me to be part of this company.

SPEAKER_00 7:16

And it's so funny because when I heard you describe that for the first time, I thought to myself, that fits, right? Because supplements are really just about fixing one little thing, like a deficiency, right? Filling a gap where activation is turning on a process, which turns on a systems, which turns on our body, which is way different. And it blows my mind how crazy cool that is. But it all starts with yellow, right? It protonum NRF2, this little yellow pill, and what it does. How would you describe what protonum NRF2 does and what oxidative stress is you see?

SPEAKER_01 7:50

Well, as I was saying, that the cell has so many different things to it that are so helpful. There's so many things that go on within the cell, and it's amazing. Everybody thinks about a cell, right? But they don't understand the mitochondria and all the actions that happen within it. And what the NRF2 pathway is, is it's the pathway of chemistry that makes our body clean itself up, okay? It it makes the cell take care of something called oxidative stress. Oxidative stress is a process in our body that we have, it's it's the fix and repair part of our body, okay? Our bodies are designed that things happen to it and then our body fixes it, and things happen to it, and the body fixes it. But as we get older, guess what? That slows way down. And the reason it slows down is because that NRF2 pathway is not activated as much as it should be. What I love about our NRF2 product is those five ingredients blended together, turn it back on. They they have given the body the ability to get rid of that trash, that oxidative stress that is something like uh it's hard to explain, but it is getting rid of the garbage that's accumulating inside of the cell. All right. So if you think about the NRF2 pathway, it's the ability for the body to get rid of its trash on its own by activating that NRF2 pathway.

SPEAKER_00 9:28

And because what we just talked about is the environment, right, has this buildup. So everybody has too much trash. Our cells get overwhelmed, right? My peace size brain, like not like Nancy's, but my peace size brain looks at this apple and is like, oh yeah, cut an apple every mom, right? We cut an apple, we put it on the counter, and in two seconds it starts browning. That's oxidation. That's like the rusting and the building up of the trash inside of our cells. And that's why symptoms start happening when our cells start to get damaged. Our cells can't run our body. So that's what Protonum NRF2 does. She says it turns on, right? Yeah. It turns on this antioxidant system and reduces those free radicals, therefore reducing oxidative stress. Nancy, talk about this because this is powerful right here. What proton really does in the third-party validation that you love so much?

SPEAKER_01 10:26

Oh man, I think the thing that really brought me to it is I knew about a lot of different nutrients and a lot of nutrients that did things, but the thing that people don't understand, there's lots of nutrient companies out there, right? And everybody's like, well, I got this and I got that or whatever. What really separated us and what really made me stop and look and go, oh my gosh, was the fact that when we go out and ascertain our raw ingredients, they test those raw ingredients for the active components. They test it at the site where we're getting those active components, the actual uh raw ingredients, then we bring it back and we test it again, then we make our product, then we test it again. Nobody else does that. And because of that, I'm so grateful because when the FDA saw that, that's why they allow us to make some of the claims. When we say we can reduce oxidative stress, that that big mess that happens in our cell by 40% in 30 days, we can consistently say that because when we ascertain those raw ingredients, we know every single time when we make that product, it's gonna give the same results. And that's what we love more than anything. And that's the part I get the most excited about.

SPEAKER_00 11:44

I agree. And so, like in comparison, because you've obviously done your research here, right? Is there a product that would come close to be able to make the claim that they lower oxidative stress 40% in 30 days?

SPEAKER_01 11:57

Uh no, I mean, you have to, you know, I mean, obviously God wants us to eat food. All right. So we're talking about eating pounds of blueberries and pounds of fruits and vegetables. And when she says pounds, that's like a pickup full. Yeah, yeah, in a day to equal what this is doing every second, a million to one every second to reduce that oxidative stress is it's just basically unheard of. And nobody else to this day has still been able to prove that they can do this. That's why we're so excited.

SPEAKER_00 12:36

It's magical. It really, really, really is incredible. I have one of the first people that I chatted to about this was my neighbor who's an orthopedic surgeon, right? And she came over and I said, listen, I've just run across a product that apparently can reduce oxidative stress by 40%. She said, No way. And I said, apparently, way. And I said, they there go to you can go to a website called Pebmed.gov and type in ProTandom and it will show you that this is true. And she says, I go to that website every day. Like I'm on that website almost daily. I said, Well, go type it in. And by the time she got off her shift that day, she went to work and came home after rounds. She called me and she said, I need this and I need it now. So that's where you can go find research if you want to look into it yourself, because Harvard has done it, American Heart Association has looked into it, right? All big, important million-dollar researching universities have looked into this for you so that you can feel confident in taking this product and what it's going to do for you. So, Nancy, how important truly do you believe it is to reduce oxidative stress in the body?

SPEAKER_01 13:48

How foundationally do you think that yeah, it it's it's truly something that sets us apart from everything else. It's what everyone else tries to do. It's, you know, it's why grandma told us to eat our vegetables. It's why we're supposed to eat all the things. But when you think about vitamin C and all those different things, they they come in and they help on a one-to-one ratio. We're a million to one taking care of, you know what? Just think of it as a bunch of little, I don't know, I think of it like little Pac-Men. I know that sounds kind of weird, but I think of it as these little Pac-Men going around ourselves eating up all the trash. And and guess what? When the part that people don't understand is the reason that we start having aging and diseases, as that trash fills up, it starts affecting our mitochondria and our genes. And when that starts happening based on our family, that gene complex is going to determine what things start breaking down when your body starts struggling with all of the oxidative stress. So, you know what? That's what I love the most, is it really truly is about activating your own body. So I don't have to care what is going on with your body, I don't have to care what your family genes are doing and breaking down because we're doing something far greater to help restore that.

SPEAKER_00 15:12

Yeah, you could well said. So Nancy mentioned mitochondria. So that product came out in 2005, and they realized while that's incredible, helping people reduce their oxidative stress, that oxidative stress and that free radical buildup, that trash building up, damages our mitochondria, right? They figured out how to activate a pathway called the protein or I'm sorry, the NRF1 pathway and developed a product to help with mitochondria biogenesis. So basically, we think of this pathway as the pathway to power. This is your power pathway, right? Because mitochondria powers every single cell in your body. Without it, nothing works right. Think about this as like your power source, your energy inside of every single cell. Nancy, why do mitochondria matter so much to your overall health?

SPEAKER_01 16:09

Well, when you take a look, look at this. Every cell in your body, heartbeats, thoughts, energy, every single thing that goes on in our body is dictated. The mitochondria is the energy of it's not the energy, it's the engine of the cell. Okay. So when we start having that oxidative stress we talked about, think about it just physically banging those mitochondria and damaging them. And when they get damaged, you know what, like anything that gets damaged, it can't do its job. And and what I love about the NRF one that is so amazing is it not only helps us to help the mitochondria be better again. So you got the NRF2 kind of cleaning up everything, so less is banging the mitochondria, but then we're actually helping the mitochondria to be stronger and better and wait for it. We even make more of them, which is so key. And that's why what we see, see where it says every thought? Guess what goes on in our brain? OMG. And so what I love is the NRF2 and the NRF1 are like the yin and the yang. They work together. One of them is taking care of the trash, and then you know what? You don't want to just have NRF one and build a bunch of mitochondria because guess what? When the mitochondria do their work, they put out a little trash. You know what? That's kind of their function. They they do a little work and like an engine that's burning gas, they put out a little bit of oxidative stress themselves. So the two of them work together to balance the cell.

SPEAKER_00 17:42

It's the best duo. Layering them on top of each other is literally going to help the cell so much because when your mitochondria struggle, you literally feel it everywhere, right? When you have depleted mitochondria, you're gonna feel all the things, all the things fatigue, damage, decline in your health. But when you have healthy mitochondria, you're gonna feel energized and abundant and thriving. Like just like oxidative stress builds up as we age, and that NRF2 pathway, our antioxidant pathway, slows down as we age, so does mitochondria decline. Mitochondria decline with age, they decline with chronic stress, they decline with inflammation. And I don't know anybody who can avoid stress all the time and avoid everything in their environment. It's it's like the environment and the yuck is happening too fast for our bodies to keep up. So I literally personally, after 10 years of looking into this and listening to so many people, like the brilliant Dr. Nancy, talk about this, is I don't know how you plan on surviving in a healthy, optimal way without these. Like that's literally how important I believe these to be. So what people are feeling is more centery energy throughout the day, better stamina, endurance, support for active aging, muscle function, all the things you want to feel every day. And people are feeling it quickly. I don't know if you're reading any of the comments in the chat, but people are starting to feel things. Sometimes they feel it quickly, and sometimes it takes a little while. But I'm telling you, these products are so effective no matter what people are dealing with. Okay. Now let's talk about the last of the three, right? Protandum NAD. This is the master regulator for aging. Like truly, it activates your production of seratuins, and it really is your pathway for longevity, really is what it is. So let's talk about NAD and how it declines with every single passing year, Nancy. Will you talk a little bit about NAD?

SPEAKER_01 19:52

Yes, absolutely. I I can't express how important NAD is and what people hear and say, they're oh yeah, NAD. No, I can go buy that down at uh the the nutrition market or whatever. Again, we're not giving NAD with this product, we're activating the body to make its own NAD, which is so much more powerful. And you can see here, look at this. By age 40, our NAD levels drop by nearly 50%. Doesn't that make sense? 60 by 80. And guess what? Remember when I talked about that DNA and those genes and being repaired? As those start breaking down, it's because NAD is being produced in our bodies slower and slower and slower.

SPEAKER_00 20:42

It's crazy to think about, right? When NAD is thriving, so are you. Plain and simple, right? But here's the deal: you don't want to just do NAD without cleaning up the trash and powering the mitochondria, right? This is, they literally kind of go one, two, three, right? So this powers your DNA repair. So your cells it that helps fix your cellular damage and before it turns into disease. I don't know if you've heard this phrase, but I love it. That's like usually what happens is your cells start feeling bad enough, then it sits, just dysfunction sets in. And when dysfunction sticks around long enough, it turns to disease, right? And that's why we really want you to focus on cell health so you don't have that progression, right? Fuels your sertuans, those are the proteins responsible for cellular longevity, and it drives energy production at the deepest level. It's it's really quite an incredible product. What people are feeling overall is immediate benefits really in their energy mood and focus. When you add in when someone layers on NAD to their life, they're like, whoa, this is awesome. They just literally start feeling it almost immediately. But it also has the ability to help you maintain healthy cholesterol levels and support a healthy vascular system. It's very Very, very important. It also improves the inflammatory response, which I think every human on the planet could benefit from improvement of. So, like Nancy said, NRF2 cleans the cells, NRF1 powers the cells, and NAD renews the cells, right? It's kind of like not one plus one plus one equals three. It's like equals seven. And it you have up-level benefits when you do all three together. That's called the tri-senergizer. Nancy, will you talk about that? What happens, the studies that happen when they studied these three together?

SPEAKER_01 22:33

I mean, basically, basically in the nutshell, it makes each one of those things 18 times more effective. Okay. So let's take a look. Do I want to have potandum NRF2? Absolutely. But look what happens when we do everything together. We're talking such a huge increase in the amounts that are able to happen. It's a synergizer, it's the turbo, if you will. Same with NRF1. When we take a look, you know what? We've got all these different genes that operate, all this different chemistry. And I don't want to get deep into this because I don't want you to have to know this. What you need to know is look at those percentages. This is why we call it Tri-Synergizer. What TriSynergizer means is that when all three of those things are added together with the different herbs that are placed together and the different enzymes that all of them together, that's 18 times more powerful than each thing by themselves. And guess what? In the end, that means that we're going to have the optimization of our cell better than you'd ever get with one of the things by themselves. The whole idea here is we're, you know, together we're better, right? Together we're better. And by having the increase in the three things put together, and this goes back to what I stated, we know the activity levels of each of the ingredients and each of these things. And when they're all put together, that's where the magic happens.

SPEAKER_00 24:09

It truly is amazing. I will tell you, if you have been taking protonum NRF2 already, which so every person on the planet should be at minimum taking Protonum NRF2, starting with yellow. It is pro it's the most important and the foundational of all of them. But when you can layer on NRF1, right, you could go ahead and immediately add NRF one to your life. But we and you can start with Protonum NRF2 and NRF1 together. But we do suggest that you do those for a month or two or three before you were to add NAD to your life because we don't want this ramp up effect to be too big for your body, right? You'll want this effect eventually. But let's be honest, when you're cleaning out that trash and boosting that mitochondria, we don't want any you to feel a detox effect, which of course you got to get that trash out of your body. So we just slow it down a little bit.

SPEAKER_01 25:01

Let me explain that too really quickly. So what happened? Because a lot of times people will get started on this and they're like, oh, this is making me sick. No, it's not that. It's all the other things going on in your body that when your system wakes up and all of a sudden it's aware. Oh my gosh, it's like the body's like, holy cow, what is all this stuff? We got to get it out of here, right? And it starts getting rid of it. And so, you know what, to your point, with the NAD, sometimes it makes it go a little too fast if they've had too many other things. If they've been on other supplements from who knows where that have things that aren't that clean, you just never know. All the different things that can add up in our bodies. And so, what I love is use expressing that because it's really important for people to understand. Sometimes we have to go a little bit as slow to help our body to be able to get caught up to itself because you know what? This stuff works, it turns back on things, and when they are aware of it, it can really make you have a little bit of detox. So just make sure you're getting lots of water in and just slow down a little bit if that does happen.

SPEAKER_00 26:09

Absolutely. Uh somebody put in the chat that NAD made her tired at first, right? And so she just had to kind of play with it a little bit. And I'll be honest, when I started, when I added NAD to my life, I had to start and stop it probably two different times. But I love what you said. I believe what was happening in my body is it was another layer of something that was recognized of like, get out of here. I don't like that. But what a blessing that is because lots of times that lives underneath all of the inflammation, all of the stuff until we our bodies can recognize that it's sitting there and it would have just grown and festered into something bigger and bigger. That's what I think is amazing. And that's why we talk about cell health is everything when it comes to optimal health. So thank you for explaining that, Nancy. Protonum Tri-Synergizer comes in two different ways from the company. You can purchase it in bottles, individual bottles like this, or the way that I love it is in a handy-dandy pack. It comes in a daily pack that you can take all three together. You get to choose which way you want it delivered to you, but it's fantastic. I can't wait for all of you to try it and learn more about what the Tri-Synergizer can do in your body and be able to tell other people about it as well because I think that's what we all need to be doing is sharing what's working for us so that our neighbors and our loved ones and our community and our family can feel better too. I will leave you with this. That is an all life vantage has to offer. We have products for solutions for everything hair care, skincare, GLP one, brain food, right? All the things. But tonight we wanted to focus on cell health, but continue to come back to Wellness Wednesday each and every week because we dive into different health topics. And at the end, the last Wednesday of every month, we will be doing a showcase. I'm highlighting different categories of products that can help you activate your body. Nancy, thank you so much for taking time out of your day to help educate all of us. We appreciate you and your beautiful brain very, very much.

SPEAKER_01 28:12

Oh, thank you so much. I hope the background wasn't too much. I apologize for that. But I will tell you, I will never ever be without these. And I just want to end with one thing. When my body was in such terrible shape and I was able to get started on this, things changed so drastically in such a short time. My doctor made me go back and get my blood work done again because he said the lab made a mistake. Okay. And so I just want to put out there, our bodies are capable. All we're doing is allowing our bodies to activate to its optimum. And I'm so very, very grateful to have the energy and and the focus and the mindset that that I'm able to have because of these. So thank you.

SPEAKER_00 29:00

Nancy, do me a favor, share. I know you will, or I wouldn't have asked. Share your age with everybody right now. I think everybody's gonna be blown away. She is a product of this product, and this is what anti-aging at its finest looks like. Nancy.

SPEAKER_01 29:16

Yes, yes, I I'm proud to call myself 72. Amazing. Amazing.

SPEAKER_00 29:22

She runs around like a teenager.

SPEAKER_01 29:25

And I'm so grateful because of this. You know what? I'm so blessed not to be on any prescriptions at at the age and time I am. You know what? The thing of it is the body activated, give us the the best opportunity to have the best life we can. Incredible.

SPEAKER_00 29:43

Thank you so much. Thank you everyone for joining us. We appreciate you. We'll see you next Wednesday.